Commentary: Acute Myocardial Response to Stretch: What We (don't) Know

Acute Myocardial Response to Stretch: What We (don't) Know

Myocardial stretch, as result of acute hemodynamic overload, is one of the most frequent challenges to the heart and the ability of the heart to intrinsically adapt to it is essential to prevent circulatory congestion. In this review, we highlight the historical background, the currently known mechanisms, as well as the gaps in the understanding of this physiological response. The systolic adap...

Bone marrow mononuclear cell therapy for acute myocardial infarction: we know what we want, but we just don't know how yet.

To understand the role of bone marrow mononuclear cells in the treatment of acute myocardial infarction, this overview offers a retrospective examination of strengths and limitations of 3 contemporaneous trials with attention to critical design features and provides an analysis of the combined data set and implications for future directions in cell therapy for acute myocardial infarction. (Circ...

Do We Know What We Do not Know? A Response to Celine Bonnet

Adopting New International Health Instruments – What Can We Learn From the FCTC?; Comment on “The Legal Strength of International Health Instruments - What It Brings to Global Health Governance?”

This Commentary forms a response to Nikogosian’s and Kickbusch’s forward-looking perspective about the legal strength of international health instruments. Building on their arguments, in this commentary we consider what we can learn from the Framework Convention on Tobacco Control (FCTC) for the adoption of new legal international health instruments.

Sucrose, High Fructose Corn Syrup 55% and Fructose, Metabolism and Potential Health Effects: What Do We Really Know?

There are a lot of discussions and controversy about sucrose and other sweeteners regarding their metabolism and health effects. These concerns are often arising by speculation based on limited data or few studies on animals. Recent controversies have arisen following the publication of a commentary suggesting a possible link between high fructose corn syrup (HFCS) consumption and obesity. Sinc...